Electronic Theses and Dissertation

Latar Belakang: Pencegahan dan tatalaksana Emergence Agitation (EA) merupakan suatu hal kompleks dan penting untuk keselamatan dan kepuasan pasien. Hingga saat ini, belum ada standar baku untuk pelayanan anestesi untuk mencegah terjadi EA. Berbagai upaya selama fase intraoperatif dapat dilakukan untuk mengurangi insidensi EA, seperti pemberian obat-obatan selama induksi dan pemeliharaan anestesi. Penelitian ini bertujuan untuk mengetahui perbedaan efektivitas dexmedetomidine 0,25mcg/kgBB, fentanyl 1mcg/kgBB dan placebo dalam mengurangi insidensi emergence agitation pada anak di instalasi bedah sentral (IBS) Rumah Sakit Umum Daerah Dr. Zainoel Abidin. Metodologi Penelitian: Penelitian ini menggunakan rancangan penelitian eksperimental posttest only three groups. Penelitian ini telah mendapat persetujuan etik. Populasi pada penelitian ini merupakan seluruh pasien anak usia 7-16 tahun yang menjalani prosedur general anesthesia di kamar operasi elektif RSUDZA. Subjek penelitian yang dipilih sesuai dengan kriteria inklusi dan eksklusi. Pada penelitian sampel dibagi menjadi 3 kelompok yaitu kelompok plasebo (kontrol), kelompok fentanyl 1mcg/kgBB dan kelompok dexmedetomidine dosis 0,25mcg/kgBB. Hasil Penelitian: Dari 53 sampel yang menjalani oeprasi elektif area kepala dan leher usia 7-16 tahun hanya 39 sampel yang memenuhi kriteria inklusi dan bersedia menjadi subjek penelitian. Berdasarkan karakteristik subjek penelitian tidak ditemukan perbedaan signifikan pada ketiga kelompok baik dari jenis kelamin, ASA, usia, dan durasi anestesi. Terdapat perbedaan yang signifikan pada variabel emergence agitation, durasi emergence dan durasi di PACU di ketiga kelompok penelitian (p

Background: Prevention and management of Emergence Agitation (EA) is a complex matter and important for patient safety and satisfaction. Until now, there is no standard for anesthesia services to prevent EA from occurring. Various efforts during the intraoperative phase can be made to reduce the incidence of EA, such as administration of drugs during induction and maintenance of anesthesia. This study aims to determine the differences in the effectiveness of dexmedetomidine 0.25 mcg/kgBW, fentanyl 1mcg/kgBW and placebo in reducing the incidence of emergence agitation in children at the Central Surgical Installation (IBS) Regional General Hospital Dr. Zainoel Abidin. Research Methodology: This study used an observational analytical research design with a categorical comparative study. This study has received ethical approval. The population in this study were all pediatric patients aged 7-16 years who underwent general anesthesia procedures in the elective operating room of RSUDZA. Research subjects were selected according to the inclusion and exclusion criteria. In this study the sample was divided into 3 groups, namely the placebo group (control), the fentanyl group 1 mcg/kgBW and the dexmedetomidine group with a dose of 0.25mcg/kgBW. Results: From 53 samples who underwent elective head and neck surgery aged 7-16 years, only 39 samples met the inclusion criteria and were willing to be research subjects. Based on the characteristics of the research subjects, no significant differences were found in the three groups in terms of gender, ASA, age, and duration of anesthesia. There were significant differences in the variables of emergence agitation, duration of emergence and duration in PACU in the three study groups (p