Electronic Theses and Dissertation

ABSTRAK

Leukosit merupakan sel darah yang diproduksi oleh jaringan hematopoietik berfungsi dalam sistem pertahanan tubuh. Penelitian ini bertujuan mengamati perbedaan jumlah leukosit dan diferensial leukosit burung merpati setelah pemasangan implan pin intramedular material bone pin pada tiap-tiap hari pengamatan. Penelitian ini menggunakan 10 ekor burung merpati jantan berumur 4-5 bulan dengan berat badan 300-500 gram yang terbagi menjadi 2 kelompok perlakuan. Semua merpati dibuat fraktur transversa pada tulang humerus, 5 merpati diimplankan pin intramedullar (P1) dan 5 merpati diimplankan dengan bone pin tulang biawak (P2). Pengambilan darah dilakukan melalui vena tibia caudalis pada hari ke 0, 3, 7 dan 14. Jumlah total leukosit, basofil dan limfosit menunjukkan perbedaan yang signifikan (P0,05) terhadap eosinofil, neutrofil dan monosit. Jumlah leukosit, basofil, neutrofil, limfosit dan monosit juga tidak menunjukkan perbedaan signifikan (P>0,05) diantara waktu pengamatan. Implan bone pin tulang biawak dan pin intramedullar menunjukkan perubahan jumlah leukosit dan differensial leukosit diantara kelompok perlakuan dan waktu pengamatan mengalami fluktuasi. Perubahan masih dalam kisaran normal sehingga masih bisa diterima oleh tubuh dan berpotensi untuk dikembangkan lagi menjadi bahan implan alternatif.



Kata kunci: leukosit, diferensial leukosit, merpati, pin intramedullar, bone pin.

ABSTRACT Leukocytes are blood cells produced by hematopoietic tissue to function in the body's defense system. This study aimed to observe the difference in the number of leucocytes and the differential of pigeon leucocytes after the intramedular pin implant of bone pin material on each observation day. This study used 10 male pigeons aged 4-5 months with a body weight of 300-500 grams which were divided into 2 treatment groups. All pigeons had transverse fractures of the humeral bone, 5 pigeons were implanted with an intramedullary pin (P1) and 5 pigeons were implanted with a monitor lizard bone pin (P2). Blood was drawn through the tibial caudal vein on days 0, 3, 7 and 14. The total number of leukocytes, basophils and lymphocytes showed a significant difference (P0.05) against eosinophils, neutrophils and monocytes. The number of leukocytes, basophils, neutrophils, lymphocytes and monocytes also did not show a significant difference (P>0.05) between the observation times. Implants of bone pin lizard bone and intramedullary pin showed changes in the number of leukocytes and differences in leukocytes between the treatment groups and the time of observation fluctuated. The changes are still within the normal range so that they can still be accepted by the body and have the potential to be developed into alternative implant materials. Keywords: leukocytes, differential leukocytes, pigeon, intramedullary pin, bone pin.