Electronic Theses and Dissertation

Kesehatan kulit dipengaruhi oleh berbagai faktor, termasuk keseimbangan mikrobiota kulit. Salah satu bakteri yang berperan dalam ekosistem kulit adalah Staphylococcus aureus, yang pada kondisi tertentu dapat memicu inflamasi dan kerusakan sawar kulit. Penelitian ini bertujuan untuk menganalisis hubungan antara kuantitas Staphylococcus aureus dengan kesehatan kulit wajah pada wanita dewasa di Kota Banda Aceh berdasarkan parameter hiperpigmentasi, hidrasi, dan kerutan kulit. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross-sectional yang dilakukan pada 48 wanita usia 30–40 tahun menggunakan sampel biologis tersimpan berupa swab kulit wajah. Kuantitas Staphylococcus aureus diukur menggunakan metode quantitative Polymerase Chain Reaction (qPCR) berdasarkan nilai cycle threshold (CT), sedangkan parameter kesehatan kulit diperoleh menggunakan Skin Analyzer Magic Mirror Plus®. Analisis data dilakukan secara univariat dan bivariat menggunakan uji korelasi sesuai distribusi data. Hasil penelitian menunjukkan rerata nilai CT Staphylococcus aureus sebesar 35,34 ± 1,84, rerata hiperpigmentasi sebesar 25,75% ± 13,56, hidrasi sebesar 63,19% ± 12,49, dan kerutan sebesar 39,17% ± 16,42. Tidak terdapat hubungan yang bermakna antara kuantitas Staphylococcus aureus dengan hiperpigmentasi (r=0,073; p=0,621), hidrasi (r=-0,183; p=0,213), maupun kerutan kulit (r=0,057; p=0,701). Disimpulkan bahwa kuantitas Staphylococcus aureus tidak berhubungan secara signifikan dengan kesehatan kulit wajah pada wanita dewasa di Kota Banda Aceh.

Skin health is influenced by various factors, including the balance of the skin microbiota. One of the bacteria that plays a role in the skin ecosystem is Staphylococcus aureus, which under certain conditions may induce inflammation and impair the skin barrier. This study aimed to analyze the relationship between the quantity of Staphylococcus aureus and facial skin health among adult women in Banda Aceh City based on skin hyperpigmentation, hydration, and wrinkle parameters. This analytical observational study employed a cross-sectional design involving 48 women aged 30–40 years using stored biological samples in the form of facial skin swabs. The quantity of Staphylococcus aureus was measured using quantitative Polymerase Chain Reaction (qPCR) based on cycle threshold (CT) values, while skin health parameters were assessed using the Magic Mirror Plus® Skin Analyzer. Data were analyzed using univariate and bivariate analyses with correlation tests according to data distribution. The results showed that the mean CT value of Staphylococcus aureus was 35.34 ± 1.84, while the mean hyperpigmentation, hydration, and wrinkle levels were 25.75% ± 13.56, 63.19% ± 12.49, and 39.17% ± 16.42, respectively. There were no significant correlations between the quantity of Staphylococcus aureus and hyperpigmentation (r = 0.073; p = 0.621), hydration (r = –0.183; p = 0.213), or wrinkles (r = 0.057; p = 0.701). In conclusion, the quantity of Staphylococcus aureus was not significantly associated with facial skin health among adult women in Banda Aceh City.