Electronic Theses and Dissertation

Kulit yang terpapar oleh paparan sinar UV dan radikal bebas dapat menyebabkan munculnya tanda penuaan yang meliputi penurunan kadar kolagen dan elastin, sehingga mengakibatkan kulit mengendur, munculnya kerutan, penurunan kelembapan dan elastisitas. Kolagen hasil ekstraksi dari tulang ikan tuna memiliki aktivitas yang dihasilkan berupa kemampuan antiaging. Penelitian ini bertujuan untuk menguji efektivitas antiaging dengan melihat adanya perbaikan terhadap parameter tanda penuaan setelah penggunaan produk face wash Ocean Pure® dengan kandungan kolagen tulang ikan tuna sirip kuning (Thunnus albacares) pada kulit wajah sukarelawan secara in vivo. Parameter yang diukur meliputi sebum, kelembapan, elastisitas, pigmentasi, dan serat kolagen dengan menggunakan alat skin analyzer EH 900-U secara kuantitatif serta kerutan secara kualitatif. Hasil uji efektivitas antiaging menunjukkan peningkatan nilai sebum, serat kolagen, elastisitas, kelembapan, dan pigmentasi dibandingkan data awal setelah dua minggu perlakuan. Hasil analisis statistik menunjukkan adanya perbedaan signifikan (p

Skin exposure to ultraviolet (UV) radiation and free radicals can accelerate the aging process, characterized by a reduction in collagen and elastin levels, leading to skin sagging, wrinkle formation, decreased moisture content, and reduced elasticity. Collagen extracted from tuna fish bones exhibits anti-aging activity and has the potential to improve skin condition. This study aimed to evaluate the anti-aging effectiveness of Ocean Pure® facial wash containing collagen derived from yellowfin tuna (Thunnus albacares) bones through in vivo assessment on the facial skin of volunteers. The evaluated parameters included sebum content, skin moisture, elasticity, pigmentation, and collagen fibers, which were quantitatively measured using the EH 900-U skin analyzer, while wrinkle appearance was assessed qualitatively. The results of the antiaging effectiveness test demonstrated increases in sebum levels, collagen fiber density, elasticity, moisture content, and pigmentation compared to baseline values after two weeks of treatment. Statistical analysis revealed significant differences (p < 0.05) in the treatment group (P) for sebum, moisture, collagen fibers, elasticity, and pigmentation. Based on these findings, it can be concluded that the Ocean Pure® anti-aging facial wash containing collagen extracted from yellowfin tuna (Thunnus albacares) bones exerts a favorable anti-aging effect, particularly in improving sebum levels, collagen fiber density, skin elasticity, and moisture content.