Electronic Theses and Dissertation

Perubahan rasa merupakan salah satu efek samping yang sering dialami oleh anak-anak penderita kanker yang menjalani kemoterapi. Perubahan persepsi rasa ini dapat memengaruhi nafsu makan dan status nutrisi pasien. Mekanisme terjadinya perubahan rasa diduga berkaitan dengan kerusakan sel pengecap dan perubahan komposisi saliva akibat obat kemoterapi. Penelitian ini bertujuan untuk mengetahui hubungan antara jenis kelamin, durasi kemoterapi, usia, dan jenis kanker terhadap perubahan rasa pada anak-anak penderita kanker yang menjalani kemoterapi. Penelitian ini bersifat analitik observasional dengan pendekatan potong lintang. Sampel penelitian terdiri dari 30 anak yang memenuhi kriteria inklusi, dengan teknik total sampling. Data karakteristik pasien diperoleh melalui wawancara dan derajat perubahan rasa diukur menggunakan Taste Alteration Scale for Children Receiving Chemotherapy (TAS-CrC). Hasil penelitian menunjukkan adanya hubungan antara durasi kemoterapi terhadap karakteristik disgeusia pada anak-anak penderita kanker yang menjalani kemoterapi berdasarkan analisis uji Mann Whitney (p < 0,05), namun Tidak terdapat hubungan antara jenis kelamin, usia, dan jenis kanker terhadap karakteristik disgeusia pada anak-anak penderita kanker yang menjalani kemoterapi (p > 0,05). Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa terdapat hubungan antara durasi kemoterapi dan tidak terdapat hubungan antara jenis kelamin, usia, dan jenis kanker terhadap karakteristik perubahan rasa pada anak-anak penderita kanker yang menjalani kemoterapi. Terdapat hubungan antara durasi kemoterapi dan perubahan rasa pada anak-anak penderita kanker yang menjalani kemoterapi.

Kata Kunci: Kanker Anak, Kemoterapi, Perubahan Rasa, TAS-CrC

Taste alteration is a common side effect experienced by children with cancer undergoing chemotherapy. This change in taste perception can significantly impact the patient's appetite and nutritional status. The mechanism behind taste alteration is thought to be related to damage to taste bud cells and changes in saliva composition caused by chemotherapy drugs. This study aims to determine the relationship between gender, duration of chemotherapy, age, and type of cancer on taste alterations in children with cancer undergoing chemotherapy. This study is an observational analytic research with a cross-sectional approach. The sample consisted of 30 children who met the inclusion criteria, selected using a total sampling technique. Patient characteristics were obtained through interviews, and the degree of taste alteration was measured using the Taste Alteration Scale for Children Receiving Chemotherapy (TAS-CrC). The results showed a significant relationship between the duration of chemotherapy and dysgeusia characteristics in children with cancer, based on the Mann-Whitney test analysis (p < 0.05). However, there was no significant relationship between gender, age, or type of cancer and dysgeusia characteristics (p > 0.05). Based on these findings, it can be concluded that while chemotherapy duration is related to taste alteration characteristics in pediatric cancer patients, gender, age, and type of cancer are not. There is a clear correlation between the duration of chemotherapy and taste alteration in children with cancer undergoing treatment. Keywords: Childhood Cancer, Chemotherapy, Taste Alteration, TAS-CrC