Electronic Theses and Dissertation

Pemanfaatan antibiotik dalam industri peternakan unggas telah menjadi hal yang sering dilakukan, untuk tujuan pengobatan penyakit, peningkatan laju pertumbuhan, maupun sebagai bahan tambahan dalam pakan guna memperbaiki produktivitas ternak. Namun demikian, penggunaan antibiotik secara berlebihan dan tidak terkontrol dapat menimbulkan dampak negatif berupa meningkatnya kejadian resistensi terhadap antibiotik. Kondisi ini menjadi perhatian serius karena bakteri patogen seperti Escherichia coli (E. coli) kerap menjadi penyebab utama infeksi pada unggas. Beberapa antibiotik yang sering digunakan dalam pengobatan infeksi akibat E. coli antara lain tetrasiklin, streptomicin, kolistin, ciprofloxacin, dan imipenem, yang memiliki kemampuan untuk menghambat maupun membunuh pertumbuhan bakteri patogen tersebut. Penelitian ini mempunyai tujuan untuk melihat presentase atau tingkat resistensi E. coli patogen isolat asal itik terhadap 5 antibiotik. Penelitian ini menggunakan metode Cross Sectional Study. Sepuluh sampel isolat Escherichia coli patogen asal itik diperiksa menggunakan metode Carter, dan uji resistensi antibiotik menggunakan metode Kirby-Bauer. Hasil uji resisten 10 sampel isolat Escherichia coli patogen terhadap antibiotik menunjukkan 20% telah resisten terhadap tetrasiklin, 50% resisten streptomicin, 100% resisten kolistin, 50% resisten ciprofloxacin, dan 30% resisten imipenem. Kesimpulan penelitian ini menunjukkan isolat bakteri E.coli dari itik yang diperoleh menunjukkan tingkat resisten yang cukup tinggi.

The use of antibiotics in the poultry industry has become a common practice, aimed at disease treatment, growth promotion, and as feed additives to improve livestock productivity. However, excessive and uncontrolled use of antibiotics can have negative impacts, particularly the increasing incidence of antibiotic resistance. This issue has become a major concern since pathogenic bacteria such as Escherichia coli (E. coli) are often the main cause of infections in poultry. Several antibiotics frequently used to treat infections caused by E. coli include tetracycline, streptomycin, colistin, imipenem, and ciprofloxacin, which have the ability to inhibit or kill the growth of pathogenic bacteria.This study aims to determine the percentage or level of resistance of pathogenic E. coli isolates from ducks to five types of antibiotics. A Cross-Sectional Study design was employed. Ten isolates of pathogenic Escherichia coli from ducks were examined using the Carter method, and antibiotic resistance testing was conducted using the Kirby-Bauer method.The results showed that among the ten isolates tested, 20% were resistant to tetracycline, 50% to streptomycin, 100% to colistin, 50% to ciprofloxacin, and 30% to imipenem. The findings indicate that E. coli isolates obtained from ducks exhibited a relatively high level of antibiotic resistance.