Electronic Theses and Dissertation

Ketahanan hidup merupakan rentang waktu sejak awal pengamatan hingga terjadinya suatu peristiwa, seperti kematian, munculnya penyakit baru, atau kekambuhan. Kanker paru merupakan salah satu penyebab utama kematian akibat kanker di dunia. Faktor-faktor yang dapat mempengaruhi ketahanan hidup pasien kanker paru seperti, usia, jenis kelamin, riwayat merokok, ECOG Performance Status, stadium kanker, dan metastasis kanker. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi ketahanan hidup 6 bulan pasien kanker paru yang menjalani kemoterapi di RSUDZA pada tahun 2024. Penelitian ini dilakukan pada bulan September-Oktober 2025 di Instalasi Rekam Medis RSUDZA. Jenis penelitian ini adalah penelitian observasional dengan teknik sampling total populasi. Analisis data menggunakan uji Chi-square dan Point/Rank Biserial pada tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa sebagian besar pasien berusia 45–59 tahun (54%), berjenis kelamin laki-laki (74%), memiliki riwayat merokok (70%), serta berada pada stadium IVa (58%). Sebanyak 50% pasien masih hidup dalam enam bulan setelah menjalani kemoterapi. Analisis statistik menunjukkan adanya hubungan antara ECOG performance status (P=0,000) dan stadium kanker (P=0,045) dengan ketahanan hidup enam bulan, sedangkan usia (P=0,480), jenis kelamin (P=0,519), riwayat merokok (P=0,537), dan metastasis (P=0,103) tidak menunjukkan hubungan dengan ketahanan hidup enam bulan. Kesimpulan, ECOG performance status dan stadium kanker berpengaruh terhadap ketahanan hidup enam bulan penderita kanker paru yang menjalani kemoterapi di RSUDZA.
Kata kunci: Kanker paru, ketahanan hidup, kemoterapi.

Survival refers to the time interval from the beginning of observation until the occurrence of a specific event, such as death, the onset of a new disease, or disease recurrence. Lung cancer is one of the leading causes of cancer-related mortality worldwide. Several factors may influence the survival of lung cancer patients, including age, sex, smoking history, ECOG performance status, cancer stage, and metastasis. This study aimed to identify the factors affecting six-month survival among lung cancer patients undergoing chemotherapy at RSUDZA in 2024. This study was conducted from September to October 2025 in the Medical Records Unit of RSUDZA. This study was an observational study using a total population sampling technique. Data were analyzed using Chi-square and Point/Rank Biserial tests, with a 95% confidence level. The results showed that most patients were aged 45–59 years (54%), male (74%), had a history of smoking (70%), and were diagnosed at stage IVa (58%). Half of the patients (50%) died within six months after undergoing chemotherapy. Statistical analysis showed a significant association between ECOG performance status (P = 0.000) and cancer stage (P = 0.045) with six-month survival. In contrast, age (P = 0.480), sex (P = 0.519), smoking history (P = 0.537), and metastasis (P = 0.103) were not significantly associated with six-month survival. In conclusion, ECOG performance status and cancer stage significantly influence the six-month survival of lung cancer patients undergoing chemotherapy at RSUDZA. Keywords: Lung neoplasms, survival rate, chemotherapy.