Electronic Theses and Dissertation

Stroke hemoragik merupakan kondisi neurologis akut dengan tingkat mortalitas dan disabilitas yang tinggi, dan berbagai faktor metabolik seperti rasio LDL/HDL diduga berperan dalam memengaruhi luaran klinis. Penelitian ini bertujuan menilai hubungan rasio LDL/HDL dengan outcome pasien stroke hemoragik di RSUD dr. Zainoel Abidin Banda Aceh. Jenis penelitian ini adalah observasional dengan desain cross sectional pada 55 pasien yang memenuhi kriteria inklusi. Data kadar LDL, HDL, skor Barthel Index, volume perdarahan, dan lokasi perdarahan diperoleh dari rekam medis serta hasil CT-Scan. Hasil penelitian menunjukkan bahwa mayoritas pasien adalah pria (56,4%), berada pada rentang usia 45–64 tahun (52,7%), memiliki rasio LDL/HDL rendah (92,7%), outcome baik berdasarkan Barthel Index (74,5%), volume perdarahan kecil (78,2%), serta lokasi perdarahan di lobar (58,2%). Hasil uji korelasi Spearman dengan α = 0,05 dan Cofidence Interval 95% menunjukkan bahwa rasio LDL/HDL tidak memiliki hubungan dengan outcome (r = –0,164; p = 0,233). Volume perdarahan menunjukkan hubungan dengan outcome (r = 0,506; p < 0,001), sedangkan lokasi perdarahan tidak menunjukkan hubungan dengan outcome (r = –0,251; p = 0,064). Kesimpulannya, rasio LDL/HDL dan lokasi perdarahan tidak memiliki hubungan dengan outcome pasien stroke hemoragik, sementara volume perdarahan berhubungan dengan outcome.
Kata kunci: Stroke hemoragik, rasio LDL/HDL, Barthel Index, outcome, volume perdarahan.

Hemorrhagic stroke is an acute neurological condition with high rates of mortality and disability, and various metabolic factors such as the LDL/HDL ratio are suspected to play a role in influencing clinical outcomes. This study aimed to assess the relationship between the LDL/HDL ratio and the outcomes of hemorrhagic stroke patients at Dr. Zainoel Abidin General Hospital, Banda Aceh. This observational study used a cross-sectional design involving 55 patients who met the inclusion criteria. Data on LDL and HDL levels, Barthel Index scores, hematoma volume, and hemorrhage location were obtained from medical records and CT-scan results. The findings showed that most patients were male (56.4%), aged 45–64 years (52.7%), had a low LDL/HDL ratio (92.7%), good outcomes based on the Barthel Index (74.5%), small hematoma volumes (78.2%), and lobar hemorrhage locations (58.2%). Spearman correlation analysis with α = 0.05 and a 95% Confidence Interval showed that the LDL/HDL ratio was not associated with outcomes (r = –0.164; p = 0.233). Hematoma volume was associated with outcomes (r = 0.506; p < 0.001), while hemorrhage location was not associated with outcomes (r = –0.251; p = 0.064). In conclusion, the LDL/HDL ratio and hemorrhage location were not significantly associated with outcomes in patients with hemorrhagic stroke, whereas hematoma volume was associated with outcomes. Keywords: Hemorrhagic stroke, LDL/HDL ratio, Barthel Index, functional outcome, hematoma volume.