Electronic Theses and Dissertation

Pneumonia merupakan inflamasi akut pada bagian distal parenkim paru yang menyebabkan konsolidasi jaringan dan menimbulkan gangguan pertukaran gas dalam paru sehingga penderita sesak napas. Salah satu pemeriksaan penunjang untuk pneumonia adalah pemeriksaan hematologi yang berfungsi untuk menilai kondisi kesehatan pasien. Profil hematologi meliputi nilai hemoglobin, hematokrit, eritrosit, trombosit, leukosit, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW), mean platelet volume (MPV), platelet distribution width (PDW), dan hitung jenis leukosit. Tujuan dari penelitian ini untuk mengetahui perbedaan kadar profil hematologi sebelum dan sesudah pengobatan antibiotik pada pasien pneumonia di RSUDZA Banda Aceh. Jenis penelitian ini adalah penelitian observational analitik dengan pendekatan retrospektif, dengan teknik nonprobability sampling. Hasil uji analisis didapatkan nilai P 0,05 pada hemoglobin, hematokrit, eritrosit, trombosit, mean corpuscular hemoglobin (MCH), mean platelet volume (MPV), platelet distribution width (PDW), neutrofil batang, neutrofil segmen, limfosit, dan monosit yang menandakan tidak adanya perbedaan signifikan setelah pengobatan antibiotik pada pasien pneumonia.

Pneumonia is an acute inflammation of the distal pulmonary parenchyma which leads to tissue consolidation and impairs gas exchange within the lungs, resulting in shortness of breath. Haematological examination serves as a supportive diagnostic tool in pneumonia patients, aiding in the assessment of overall health status. The haematological profile includes parameters such as haemoglobin, haematocrit, erythrocyte count, platelet count, leukocyte count, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), red cell distribution width (RDW), mean platelet volume (MPV), platelet distribution width (PDW), and differential leukocyte count. The objective of this study was to investigate the differences in haematological profile parameters before and after antibiotic therapy in patients with pneumonia at RSUDZA Banda Aceh. This research employed an observational analytic design with a retrospective approach and utilised a non-probability sampling technique. Statistical analysis revealed a P-value of 0.05 were observed for haemoglobin, haematocrit, erythrocytes, platelets, MCH, MPV, PDW, basophils, band neutrophils, segmented neutrophils, lymphocytes, and monocytes, suggesting no statistically significant differences in these parameters post-antibiotic.