Electronic Theses and Dissertation

Pengaruh Oxymetazoline HCl 0,05% Semprot Hidung Preoperatif Terhadap Visualisasi dan Perdarahan Intraoperasi Endoscopic Sinus Surgery di RSUD Dr. Zainoel Abidin Banda Aceh

Oleh : Oktaria Denantika

ABSTRAK
Latar Belakang: Endoscopic sinus surgery (ESS) memerlukan kontrol perdarahan yang baik agar visualisasi lapangan operasi memadai. Dekongestan Oxymetazoline HCl 0,05% semprot hidung dengan efek vasokonstriksi diyakini dapat memaksimalkan lapangan operasi dan mengurangi jumlah perdarahan intraoperasi. Tujuan: mengetahui pengaruh Oxymetazoline HCl 0,05% semprot hidung 1 jam preoperatif terhadap visualisasi dan jumlah perdarahan intraoperasi ESS di RSUDZA Banda Aceh. Metode: Penelitian eksperimental dengan desain cross sectional pada pasien ESS dari Juni – November 2024. Kelompok sampel disemprot Oxymetazoline HCl 0.05% 1 jam preoperatif dan data sekunder kelompok pembanding dari rekam medis dengan jumlah sebanyak kelompok sampel. Penilaian visualisasi lapangan operasi dengan skala Boezaart dan jumlah perdarahan intraoperasi dengan cara mengukur jumlah darah yang tertampung di tabung suction lalu dikurangi dengan jumlah cairan NaCl 0.9% yang digunakaan selama operasi. Data dianalisa menggunakan uji Chi- Square test dan uji Mann whitney. Hasil: Analisa dari 30 sampel didapatkan pengaruh Oxymetazoline HCl 0.05% semprot hidung mempunyai pengaruh yang bermakna terhadap visualisasi lapangan operasi (p=0.000) dan jumlah perdarahan intraoperasi (p=0.000). Kesimpulan: Oxymetazoline HCl 0.05% semprot hidung mempunyai pengaruh memaksimalkan visualisasi lapangan operasi dan dapat menurunkan rata-rata jumlah perdarahan selama prosedur ESS.

Kata Kunci: Endoscopic sinus surgery, Oxymetazoline HCl 0.05%, skala Boezaart

Effect Of Preoperative 0.05% Oxymetazoline HCl Nasal Spray on Intraoperative Visualization And Bleeding in Endoscopic Sinus Surgery At Dr. Zainoel Abidin General Hospital Banda Aceh By: Oktaria Denantika ABSTRACT Background: Effective control of bleeding is crucial for optimal visualization during Endoscopic sinus surgery (ESS), especially in terms of operational surgical field. Oxymetazoline HCl 0.05% which is a decongestant nasal spray with vasoconstriction effect, is believed to maximize the surgical field and reduce the loss of intraoperative bleeding. Objective: To determine the effect of Oxymetazoline HCl 0.05% nasal spray 1 hour preoperative on the visualization and amount of intraoperative bleeding of ESS at Banda Aceh Hospital. Methods: An Experimental study with a cross sectional design in ESS patients from June – November 2024. The sample group was sprayed with Oxymetazoline HCl 0.05% 1 hour preoperative and the control group's secondary data from medical records with as many as the sample group. Assessment of the visualization of the surgical field with the Boezaart scale and the amount of intraoperative bleeding by measuring the amount of blood stored in the suction tube and then subtracted by the amount of 0.9% NaCl fluid used during surgery. The data was analyzed using the Chi-Square test and the Mann whitney test. Results: Analysis of 30 cases demonstrated that preoperative administration of Oxymetazoline HCl 0.05% nasal spray significantly improved surgical field visualization (p=0.000) and reduced intraoperative blood loss (p=0.000). Conclusion: Preoperative use of Oxymetazoline HCl 0.05% nasal spray enhances surgical field clarity and significantly decreases bleeding during ESS. Keyword: Endoscopic sinus surgery, Oxymetazoline HCl 0.05%, Boezaart Scale