Electronic Theses and Dissertation

Latar Belakang: Letak nasofaring tersembunyi dan sulit diperiksa dengan alat sederhana, karsinoma nasofaring sering kali datang ke pusat kesehatan dengan stadium lanjut, maka diperlukan instrumen anamnesis dan pemeriksaan fisik yang bisa menilai suatu dugaan karsinoma nasofaring yaitu dengan digby score. Tujuan: Mengetahui kesesuaian digby score dengan hasil histopatologi pada pasien dugaan karsinoma nasofaring. Metode: Penelitian ini adalah observasional analitik dilakukan secara prospektif. Penelitian dilakukan di poliklinik T.H.T.K.L RSUDZA sejak bulan Januari 2024 sampai Juni 2024 pada penderita dugaan karsinoma nasofaring. Tahapan yang dilakukan berupa anamnesis, pemeriksaan fisik dan penentuan digby score kemudian mencatat Hasil patologi anatomi. Analisis kesesuaian menggunakan uji Kappa dan dilanjutkan dengan menghitung senstivitas dan spesifisitas digby score. Hasil: Didapatkan 31 penderita dugaan karsinoma nasofaring didapatkan insiden laki-laki tinggi (64,5%), kelompok usia terbanyak 45-59 tahun (41,9%), dengan faktor risiko utama merokok dan konsumsi ikan asin yaitu 45,2% tiap responden. Mayoritas hasil histopatologi karsinoma nasofaring menunjukan tipe Keratinizing Squamous Cell Carcinoma (WHO tipe I) dan Non-Keratinizing Squamous Cell Carcinoma (WHO tipe II), masing-masing sebesar 32,3%. Digby score ≥50 menunjukkan kesesuaian yang tinggi dengan hasil histopatologi, dengan nilai sensitivitas 96,2% dan spesifisitas 60%. Akurasi digby score mencapai 90,3%. Berdasarkan nilai Kappa 0,611; Nilai p = 0,001 menunjukan adanya kesesuaian yang tinggi antara digby score dan hasil biopsi histopatologi dalam mendeteksi karsinoma nasofaring. Kesimpulan: Digby score dapat dijadikan intrumen untuk diagnostik awal dugaan karsinoma nasofaring.

Kata kunci: Karsinoma nasofaring, digby score, histopatologi, biopsi.

Background : The location of the nasopharynx is hidden and difficult to examine with simple tools, nasopharyngeal carcinoma often comes to health centers in advanced stages, so an anamnesis and physical examination instrument is needed that can assess suspected nasopharyngeal carcinoma, namely the Digby score. Objective: To determine the suitability of digby score with histopathology results in patients with suspected nasopharyngeal carcinoma . Methods: This study is an observational analytic study conducted prospectively . The study was conducted at the ENT-HNS polyclinic of RSUDZA from January 2024 to June 2024 in patients with suspected nasopharyngeal carcinoma. The stages carried out were anamnesis, physical examination and determination of the digby score then recording the results of anatomical pathology. The suitability analysis used u Kappa test and continued by calculating the sensitivity and specificity of the digby score . Results: It was found that 3 1 patients with suspected nasopharyngeal carcinoma had an incident. man high ( 64.5 %), the largest age group is 45-59 years (41.9%), with the main risk factors smoking and consumption of salted fish, namely 45.2% of each respondent . The majority results histopathology of nasopharyngeal carcinoma shows type Keratinizing Squamous Cell Carcinoma (WHO type I) and Non-Keratinizing Squamous Cell Carcinoma (WHO type II) was 32.3%. Di gby s core ≥ 50 showed high agreement with histopathology results , with a sensitivity value of 96.2% and a specificity of 60%. The accuracy of di gby s core reached 90.3% . Based on the Kappa value of 0.61 1; p value = 0.001 indicates a high agreement between the Digby 's core and histopathology biopsy results in detecting nasopharyngeal carcinoma . Conclusion: Digby score can be used as an instrument for early diagnosis of suspected nasopharyngeal carcinoma. Keywords : Nasopharyngeal carcinoma, Digby score , histopathology, biopsy.