Electronic Theses and Dissertation

Sediaan facial wash atau sabun pembersih wajah merupakan sediaan kosmetik perawatan kulit wajah yang rutin digunakan setiap hari sebagai pembersih. Salah satu bentuk sediaan yang sering digunakan dalam sediaan kosmetik ialah gel. Penelitian ini bertujuan untuk memformulasikan sediaan facial wash dengan kombinasi minyak nilam fraksi ringan, ekstrak akar manis, kolagen dan niacinamide yang memenuhi persyaratan mutu fisik sediaan dan mengetahui hasil uji iritasi serta uji cemaran logam berat dan mikroba dari formula sediaan facial wash. Zat aktif minyak nilam fraksi ringan didapatkan dari Atsiri Research Center (ARC) Universitas Syiah Kuala Banda Aceh serta ekstrak akar manis, kolagen dan niacinamide diperoleh dari PT. Focustindo Cemerlang Bogor. Facial wash ini diformulasikan dengan menggunakan zat aktif (formula 1) dan tanpa menggunakan zat aktif (formula 0). Hasil dari pengujian kedua formula ini adalah sediaan facial wash yang memiliki warna bening kekuningan cerah dan bening kekuningan dengan bau khas Oceania serta tekstur sedikit kental yang homogen. Kedua formula memenuhi rentang pH yang aman bagi kulit yaitu 6,5-6,3. Viskositas dari kedua formula masih berada dalam rentang viskositas yang baik yaitu 853.0-595.0 cP. Daya busa dari formula memenuhi rentang daya busa sediaan facial wash yaitu 8-7,8 cm. Pengujian stabilitas (cycling test) dan uji sentrifugasi didapatkan bahwa sediaan tidak mengalami pemisahan fase dan terjadi perubahan stabilitas pada pH, viskositas, dan daya busa, namun masih berada dalam rentang persyaratan. Uji iritasi yang dilakukan terhadap 6 panelis menunjukkan tidak adanya tanda iritasi yang terjadi seperti edema, eritema dan gatal pada kulit panelis. Pada pengujian cemaran logam berat dan mikroba terdeteksi facial wash mengandung senyawa merkuri namun masih dikatakan aman karna dibawah rentang limit of quantification (LOQ).
Kata kunci: Facial wash, minyak nilam fraksi ringan, ekstrak akar manis, kolagen, niacinamide

Facial wash preparation or facial cleansing soap is a cosmetic preparation for facial skin care that is routinely used every day as a cleanser. One of the dosage forms that is often used in cosmetic preparations is gel. This study aims to formulate facial wash preparations with a combination of light fraction patchouli oil, liquorice extract, collagen and niacinamide that meet the physical quality requirements of the preparation and determine the results of irritation tests and heavy metal and microbial contamination tests of facial wash preparation formulas. The active substance of patchouli oil light fraction was obtained from Atsiri Research Center (ARC) Syiah Kuala University Banda Aceh and liquorice extract, collagen and niacinamide were obtained from PT Focustindo Cemerlang Bogor. This facial wash was formulated using active substances (formula 1) and without using active substances (formula 0). The results of testing these two formulas are facial wash preparations that have a bright yellowish translucent color and yellowish translucent with a distinctive Oceania odor and a homogeneous slightly thick texture. Both formulas met the skin-safe pH range of 6.5-6.3. The viscosity of both formulas was within the good viscosity range of 853.0-595.0 cP. The foam power of the formula meets the range of foam power of facial wash preparations, namely 8-7.8 cm. Stability testing (cycling test) and centrifugation test found that the preparation did not experience phase separation and changes in stability occurred in pH, viscosity, and foamability, but were still within the required range. The irritation test conducted on 6 panelists showed no signs of irritation such as edema, erythema and itching on the panelists' skin. In the heavy metal and microbial contamination test, it was detected that the facial wash contained mercury compounds but was still considered safe because it was below the limit of quantification (LOQ) range. Keywords: Facial wash, light fraction of patchouli oil, licorice root extract, collagen, niacinamide.