Electronic Theses and Dissertation

Infeksi nosokomial (Hospital Acquired Infection) merupakan infeksi yang didapatkan di tempat pelayanan kesehatan. Acinetobacter baumannii merupakan salah satu bakteri penyebab HAIs. Peningkatan infeksi Acinetobacter baumannii pada pasien di rumah sakit diikuti dengan peningkatan resistensi terhadap berbagai antibiotik. Penelitian ini bertujuan untuk mengidentifikasi dan mengetahui antibiogram bakteri Acinetobacter baumannii yang diisolasi dari spesimen darah pasien rawat inap di RSUD dr. Zainoel Abidin. Jenis penelitian ini merupakan penelitian deskriptif, data dikumpulkan dari September 2020 hingga September 2022. Pengambilan sampel didapat dari data pasien rawat inap sebanyak 43 pasien yang masuk dalam kriteria inklusi. Identifikasi dan uji sensitivitas antibiotik dilakukan dengan menggunakan alat VITEK® 2 Compact. Data hasil penelitian dianalisis dengan menghitung persentase dan antibiogram disajikan dalam bentuk tabel dan gambar. Hasil penelitian ini diperoleh 43 isolat Acinetobacter baumannii. Distribusi Acinetobacter baumannii berdasarkan ruang rawat inap tertinggi berasal dari ruang ICU (23,25%). Distribusi Acinetobacter baumannii tertinggi berdasarkan usia berada pada kelompok usia lansia 46-65 tahun (44,18%) dan berdasarkan jenis kelamin didominasi oleh laki-laki (55,81%). Antibiogram Acinetobacter baumannii menunjukkan bahwa tingkat sensitivitas Acinetobacter baumannii terhadap antibiotik Amikacin, Doxycycline dan Cefoperazone-Sulbactam, Tobramycin berada antara 60-80% sedangkan Gentamicin, Levofloxacin, Meropenem, Imipenem, Cefotaxime, Ceftriaxone, Doripenem, Piperacillin-Tazobactam dan Ceftazidime berada di bawah 50%, hanya Polymyxin B yang masih sensitif 100%. Hasil penelitian ini menunjukkan bahwa Acinetobacter baumannii di RSUD dr. Zainoel Abidin sudah resisten terhadap sejumlah antibiotik.


Kata Kunci : Hospital Acquired Infection, Acinetobacter baumannii, spesimen darah, antibiogram

Nosocomial infection (Hospital Acquired Infection) is an infection that is acquired in a health care setting. Acinetobacter baumannii is one of the bacteria that cause HAIs. The increase in Acinetobacter baumannii infection in patients in hospitals is followed by an increase in resistance to various antibiotics. This study aims to identify and determine the antibiogram of Acinetobacter baumannii bacteria isolated from blood specimens of inpatients at RSUD dr. Zainoel Abidin. This type of research is descriptive research, data were collected from September 2020 to September 2022. Sampling was obtained from inpatient data as many as 43 patients who fit the inclusion criteria. Identification and antibiotic sensitivity tests were carried out using the VITEK® 2 Compact tool. The research data were analyzed by calculating percentages and antibiograms presented in the form of tables and figures. The results of this study obtained 43 isolates of Acinetobacter baumannii. The distribution of Acinetobacter baumannii based on the highest inpatient room came from the ICU room (23.25%). The highest distribution of Acinetobacter baumannii based on age was in the elderly age group 46-65 years (44.18%) and based on gender was dominated by men (55.81%). The antibiogram of Acinetobacter baumannii showed that the sensitivity level of Acinetobacter baumannii to antibiotics Amikacin, Doxycycline and Cefoperazone-Sulbactam, Tobramycin was between 60-80% while Gentamicin, Levofloxacin, Meropenem, Imipenem, Cefotaxime, Ceftriaxone, Doripenem, Piperacillin-Tazobactam and Ceftazidime were below 50%, only Polymyxin B was still sensitive 100%. The results of this study indicate that Acinetobacter baumannii in RSUD dr. Zainoel Abidin is resistant to a number of antibiotics. Keywords : Hospital Acquired Infection, Acinetobacter baumannii, blood specimen, antibiogram