Electronic Theses and Dissertation

Abstrak latar belakang: human immunodeficiency virus (hiv) merupakan masalah kesehatan global yang menurunkan imunitas melalui kerusakan sel cd4+ dan meningkatkan risiko infeksi oportunistik. malnutrisi memperburuk progresivitas penyakit, namun hubungan status gizi dengan cd4+ dan viral load masih menunjukkan hasil yang inkonsisten sehingga perlu diteliti lebih lanjut. tujuan penelitian: mengetahui hubungan status gizi terhadap jumlah cd4+ dan viral load pada pasien hiv. metode penelitian: penelitian analitik observasional dengan desian potong lintang. sampel penelitian merupakan pasien hiv yang dirawat di rumah sakit dr. zainoel abidin banda aceh pada periode juli 2025-desember 2025. hasil: sebanyak 56 pasien dengan hiv diikutsertakan dalam penelitian ini, dengan mayoritas memiliki status gizi kurang (48,2%). sebagian besar subjek memiliki cd4+ 0,05). kesimpulan: status gizi berdasarkan imt menunjukkan hubungan signifikan terhadap jumlah cd4+ namun tidak berhubungan dengan viral load pasien dengan hiv. status gizi berdasarkan tlc tidak menunjukkan hubungan signifikan terhadap cd4+ dan viral load. kata kunci: human immunodeficiency virus, status gizi, indeks massa tubuh, total limfosit count, cd4+, viral load

ABSTRACT Background: Human Immunodeficiency Virus (HIV) is a global health problem that reduces immune function through CD4+ cell depletion and increases the risk of opportunistic infections. Malnutrition worsens disease progression. However, the relationship between nutritional status, CD4+ count, and viral load remains inconsistent and requires further investigation. Objective: This study aimed to determine the association between nutritional status and CD4+ count and viral load in patients with HIV infection. Methods: An analytical observational study with a cross-sectional design was conducted. The study samples were patients with HIV treated at dr. Zainoel Abidin General Hospital, Banda Aceh, from July 2025 to December 2025. Results: A total of 56 patients were included, with most presenting poor nutritional status (48.2%). The mean CD4+ count was 80.03 cells/µL, and most patients had CD4+ 0.05). Conclusion: BMI was significantly associated with CD4+ count. Nutritional status categories based on BMI not associated with CD4+ count and viral load in patients with HIV infection. Nutritional status categories based on TLC showed no significant association with either CD4+ count or viral load. Keywords: Human Immunodeficiency Virus, Nutritional Status, Body Mass Index, Total Lymphocyte Count, CD4+, Viral Load.