Electronic Theses and Dissertation

Preeklampsia merupakan salah satu komplikasi kehamilan dengan morbiditas dan mortalitas tinggi, yang ditandai oleh disfungsi endotel, inflamasi sistemik ditandai dengan peningkatan interleukin-6 dan gangguan fungsi ginjal. penelitian ini bertujuan untuk mengetahui perbandingan kadar interleukin-6 (il-6) dan serum kreatinin dengan kejadian preeklampsia pada ibu hamil. desain penelitian adalah komperatif study dengan 68 sampel, terdiri atas 34 ibu hamil preeklampsia dan 34 kehamilan normal yang dipilih di rsud dr. zainoel abidin banda aceh. pemeriksaan kadar il-6 dan kreatinin dilakukan melalui analisis serum, kemudian hasilnya dianalisis menggunakan uji statistik komparatif dan regresi logistik. hasil penelitian menunjukkan median kadar il-6 pada kelompok preeklampsia adalah 16,05 pg/ml (rentang 1,91–85,2), lebih tinggi signifikan dibandingkan kelompok normal 3,71 pg/ml (rentang 1,5–36,7) (p

Preeclampsia is a pregnancy complication with high morbidity and mortality, characterized by endothelial dysfunction, systemic inflammation marked by increased interleukin-6, and impaired renal function. This study aimed to determine the comparison of interleukin-6 (IL-6) and serum creatinine levels with the incidence of preeclampsia in pregnant women. The study design was a study comperative with 68 samples, consisting of 34 pregnant women with preeclampsia and 34 with normal pregnancies selected at Dr. Zainoel Abidin General Hospital in Banda Aceh. IL-6 and creatinine levels were measured through serum analysis, and the results were analyzed using comparative statistical tests and logistic regression. The results showed that the median IL-6 level in the preeclampsia group was 16.05 pg/mL (range 1.91–85.2), which was significantly higher than that in the normal group, which was 3.71 pg/mL (range 1.5–36.7) (p