Electronic Theses and Dissertation

Stenotrophomonas maltophilia merupakan bakteri gram-negatif oportunistik penyebab infeksi nosokomial, terutama pada pasien dengan penggunaan alat medis invasif. data lokal terkait distribusi dan kepekaan antibiotiknya masih terbatas. penelitian ini bertujuan untuk mengetahui distribusi dan sensitivitas antibiotik stenotrophomonas maltophilia berdasarkan spesimen klinik, usia, jenis kelamin, dan ruang rawat di rsud dr. zainoel abidin banda aceh. penelitian ini menggunakan metode observasi laboratorium dengan desain cross-sectional. data diambil dari laboratorium mikrobiologi klinik rsud dr. zainoel abidin secara retrospektif januari 2021 hingga mei 2025 dan secara prospektif juni hingga agustus 2025. bakteri diisolasi pada media macconkey agar dan dilakukan identifikasi serta uji sensitivitas antibiotik menggunakan alat otomatis vitek® 2 compact. hasil penelitian ini ditemukan 89 isolat stenotrophomonas maltophilia. distribusi frekuensi stenotrophomonas maltophilia berdasarkan spesimen klinik paling banyak ditemukan pada spesimen sputum yaitu 30,33%, diikuti dengan ett 28,08% dan urin 13,48%. berdasarkan jenis kelamin dan usia paling banyak pada laki-laki yaitu 76,19% dengan rentang usia 40 – 59 sebanyak 32,58%. distribusi stenotrophomonas maltophilia berdasarkan ruang rawat paling banyak ditemukan di ruang rawat icu 21,34%. uji sensitivitas antibiotik stenotrophomonas maltophilia hanya menghasilkan satu jenis antibiotik yang terdeteksi, yaitu levofloxacin. hasil pengujian menunjukkan bahwa 79,78% isolat stenotrophomonas maltophilia masih sensitif terhadap levofloxacin. kata kunci: antibiotik, sensitivitas, spesimen klinik, stenotrophomonas maltophilia

Stenotrophomonas maltophilia is a Gram-negative opportunistic bacterium that causes nosocomial infections, particularly in patients with the use of invasive medical devices. Local data regarding its distribution and antibiotic susceptibility remain limited. This study aimed to determine the distribution and antibiotic sensitivity of Stenotrophomonas maltophilia based on clinical specimens, age, sex, and hospital wards at Dr. Zainoel Abidin General Hospital, Banda Aceh. This research employed a laboratory observational method with a cross-sectional design. Data were collected retrospectively from the Clinical Microbiology Laboratory of Dr. Zainoel Abidin General Hospital from January 2021 to May 2025, and prospectively from June to August 2025. The bacteria were isolated on MacConkey Agar media, followed by identification and antibiotic susceptibility testing using the automated VITEK® 2 Compact system. The study identified 89 isolates of Stenotrophomonas maltophilia. The highest frequency distribution based on clinical specimens was found in sputum 30.33%, followed by endotracheal tube (ETT) specimens 28.08% and urine 13.48%. Based on sex and age, the majority were males 76.19% within the age range of 40–59 as much 32.58%. Distribution by hospital ward showed the highest prevalence in the Intensive Care Unit (ICU) 21.34%. The antibiotic susceptibility test for Stenotrophomonas maltophilia detected only one type of antibiotic, namely levofloxacin. The results showed that 79.78% of Stenotrophomonas maltophilia isolates remained sensitive to levofloxacin. Keywords: Antibiotics, sensitivity, clinical specimens, Stenotrophomonas maltophilia