Electronic Theses and Dissertation

Kesesuaian usg tiroid (klasifikasi acr ti-rads) dan fnab (tbsrtc) preoperatif dengan histopatologi paskaoperatif pada nodul tiroid oleh: muhammad iqbal abstrak latar belakang: nodul tiroid adalah lesi di dalam kelenjar tiroid secara radiologis berbeda dari parenkim disekitarnya. usg dan fnab adalah modalitas pemeriksaan yang tersedia di hampir seluruh fasilitas pelayanan kesehatan tingkat daerah maupun regional. penegakan diagnosis yang akurat, penilaian pra operasi dan pengambilan sampel jaringan penting untuk meminimalkan temuan negatif palsu dan meminimalisir intervensi bedah yang tidak perlu. tujuan: mengetahui kesesuaian gambaran usg berdasarkan klasifikasi acr ti- rads dan fnab berdasarkan klasifikasi tbsrtc preoperatif dengan histopatologi paska operatif pada nodul tiroid. metode: penelitian ini merupakan studi komparatif dengan desain observasional analitik dan pendekatan cross sectional. seluruh pasien nodul tiroid yang dioperasi dan memenuhi kriteria inklusi ditelusuri data hasil usg, fnab preoperatif dan histopatologi paskaoperatif. analisis data uji kesesuaian kategorik antar variabel berupa uji kappa dan chi-square dengan menggunakan software spss. analisis kemaknaan diagnostik mencakup akurasi sensitifitas, spesifisitas, nilai duga positif dan nilai duga negatif. hasil: didapatkan 91 sampel dengan rerata usia pasien nodul tiroid jinak 42,53 ± 12,07 tahun dan ganas 47,24 ± 15,44 tahun, jenis kelamin perempuan 80,22% dan laki-laki 19,78%. hasil pemeriksaan usg jinak 45,06% dan ganas 54,94%, fnab jinak 75,82% dan 24,18%, histopatologi paskaoperatif jinak 75,82% dan ganas 24,18%. terdapat kesesuaian usg tiroid (acr ti-rads) preoperatif dengan histopatologi paskaoperatif dengan nilai kappa 0,311 (p value

Background: Thyroid nodules are lesions in the thyroid gland that are radiologically different from the surrounding parenchyma. USG and FNAB are examination modalities available in almost all local and regional health care facilities. Accurate diagnosis, preoperative assessment and tissue sampling are important to minimize false negative findings and minimize unnecessary surgical interventions. Objective: To determine the concordance of ultrasound images based on ACR TI- RADS classification and FNAB based on TBSRTC classification preoperatively with postoperative histopathology in thyroid nodules. Methods: This study was a comparative study with analytic observational design and cross sectional approach. All thyroid nodule patients who were operated under surgical and met the inclusion criteria were searched for data on the results of ultrasound, preoperative FNAB and postoperative histopathology. Data analysis of categorical concordance test between variables in the form of Kappa and chi- square tests using SPSS software. Diagnostic significance analysis included sensitivity accuracy, specificity, positive predictive value and negative predictive value. Results: There were 91 samples with mean age of benign thyroid nodule patients 42.53 ± 12.07 years and malignant 47.24 ± 15.44 years, female gender 80.22% and male 19.78%. The results of ultrasound examination were benign 45.06% and malignant 54.94%, FNAB benign 75.82% and 24.18%, postoperative histopathology benign 75.82% and malignant 24.18%. There was concordance of preoperative thyroid ultrasound (ACR TI-RADS) with postoperative histopathology with a kappa value of 0.311 (P value