Electronic Theses and Dissertation

Sinar ultraviolet dapat menyebabkan kerusakan kulit, penuaan dini, bahkan kanker kulit. penggunaan lotion yang mengandung senyawa yang mampu melindungi kulit dari sinar matahari (sunscreen) dan mampu memantulkan dan menyerap sinar uv. formulasi dan uji aktivitas sunscreen ekstrak n-heksana buah nypa fruticans wurmb. dilakukan dengan tujuan untuk mengetahui aktivitas sunscreen serta untuk mengetahui sifat fisik yang ada di dalam lotion tersebut. ekstrak n-heksana diperoleh melalui metode maserasi dan menghasilkan ekstrak seberat 10,26 g dengan rendemen sebanyak 1,036%. nilai sun protection factor (spf) ekstrak n-heksana pada konsentrasi 2; 2,5; 5; 7,5; dan 12% berturut-turut adalah 31,063 ±0,1360; 32,023 ±0,3110; 33,846 ±0,2595; 34,273 ±0,2063; 35,257 ±0,1042. nilai sun protection factor (spf) lotion adalah 25,456 ± 0,0561; 26,432 ± 0,0954; 30,186 ± 0,2385; 32,276 ± 0,0670; 32, 823 ± 0,1468. nilai spf tertinggi pada konsentrasi 12% baik dari ekstrak dan lotion. hasil pengujian sifat fisik lotion ekstrak n-heksana memenuhi ketentuan sni. bedasarkan hasil gc-ms senyawa dominan pada esktrak adalah yaitu cis 9,12-octadecadienoic acid, i-(+)-ascorbic acid 2,6-dihexadecanoate, dan cis-vaccenic acid. kata kunci: suncreen, kulit, sinar uv, lotion, nypa fruticans wurmb.

Ultraviolet rays can cause skin damage, premature aging, and even skin cancer. The use of lotions containing bioactive compounds that can protect the skin from sunlight (sunscreen) and can reflect and absorb UV rays. Formulation and sunscreen activity testing of n-hexane extract of Nypa fruticans Wurmb. fruit were carried out with the aim of determining sunscreen activity and to determine the physical properties contained in the lotion. The n-hexane extract was obtained through the maceration method and produced an extract weighing 10.26 g with a yield of 1.036%. The sun protection factor (SPF) values of n-hexane extract at concentrations of 2; 2.5; 5; 7.5; and 12% were respectively 31.063 ± 0.1360; 32.023 ± 0.3110; 33.846 ± 0.2595; 34.273 ± 0.2063; 35.257 ± 0.1042. Meanwhile, the sun protection factor (SPF) value of the lotion was 25.456 ± 0.0561; 26.432 ± 0.0954; 30.186 ± 0.2385; 32.276 ± 0.0670; 32, 823 ± 0.1468. The highest SPF value was at a concentration of 12% for both the extract and lotion. The results of testing the physical properties of the n-hexane extract lotion met SNI requirements. Based on the GC-MS results, the dominant compounds in the extract were cis 9,12-octadecadienoic acid, I-(+)-ascorbic acid 2,6-dihexadecanoate, and cis-vaccenic acid. Keywords: Sunscreen, skin, UV rays, lotion, Nypa fruticans Wurmb.