Electronic Theses and Dissertation

ABSTRAK

Penelitian ini bertujuan untuk menguji daya hambat bakteri campuran ekstrak metanol buah pepaya (Carica papaya L.) dengan minyak kayu putih (Melaleuca cajuputi Powell) yang diformulasikan dalam bentuk sediaan masker peel off serta pengujian organoleptik masker tersebut. Penelitian ini menggunakan metode ekstraksi maserasi dengan pelarut metanol dan metode cakram blank disk untuk pengujian antibakteri. Analisis data diolah menggunakan analisis Kruskal Wallis dengan variasi konsentrasi ekstrak buah pepaya (Carica papaya L.) adalah 0%, 3%, 6%, 9%, dan 12% serta variasi konsentrasi minyak kayu putih (Melaleuca cajuputi Powell) ialah 0%, 1%, 2%, 3%, dan 4% dengan 3 pengulangan. Hasil pengujian antibakteri menunjukkan bahwa zona hambat bakteri yang terbesar terdapat pada perlakuan formulasi K5P5 diikuti oleh K5P4, K5P3, K5P2, dan K5P1 dengan masing-masing zona hambat sebesar 6,9 mm, 6,6 mm, 6,4 mm, 6,1 mm, dan 5,5 mm. Hasil pengujian organoleptik menunjukkan bahwa formulasi campuran ekstrak pepaya dan minyak kayu putih memiliki tekstur yang semi solid atau kental, bau menyengat khas minyak kayu putih, memiliki daya lekat yang baik pada kulit, tidak terasa panas, serta mudah dikelupas.

Kata Kunci: Pepaya, minyak kayu putih, Staphylococcus aureus, antibakteri, masker peel off

ABSTRACT This study aimed to test the bacterial inhibition of a mixture of methanol extract of papaya (Carica papaya L.) with eucalyptus oil (Melaleuca cajuputi Powell) which was formulated in the form of a peel off mask and organoleptic testing of the mask. This research uses maceration extraction method with methanol solvent and blank disk method for antibacterial testing. Data analysis was processed using Kruskal Wallis analysis with variations in the concentration of papaya fruit extract (Carica papaya L.) were 0%, 3%, 6%, 9%, and 12% and the concentration variation of eucalyptus oil (Melaleuca cajuputi Powell) was 0 %, 1%, 2%, 3%, and 4% with 3 repetitions. The antibacterial test results showed that the largest bacterial inhibition zone was found in the K5P5 formulation treatment followed by K5P4, K5P3, K5P2, and K5P1 with each inhibition zone of 6.9 mm, 6.6 mm, 6.4 mm, 6.1 mm, and 5.5 mm. The results of organoleptic testing showed that the formulation of a mixture of papaya extract and eucalyptus oil had a semi-solid or thick texture, a pungent odor typical of eucalyptus oil, had good adhesion to the skin, did not feel hot, and easily peeled off. Keywords: Papaya, eucalyptus oil, Staphylococcus aureus, antibacterial, peel off mask