Electronic Theses and Dissertation

ABSTRAK
Pandemi yang disebabkan oleh infeksi virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) atau yang lebih dikenal dengan Coronavirus Disease 2019 (COVID-19) masih terus berlangsung diberbagai negara. Beberapa penelitian melaporkan adanya prevalensi pasien COVID-19 dengan komorbid yang tinggi. Selain itu komorbiditas juga menjadi salah satu faktor yang diduga meningkatkan risiko keparahan pada penyakit serta luaran yang buruk. Penelitian ini bertujuan untuk mengetahui hubungan faktor komorbid dengan luaran pasien COVID-19. Jenis penelitian ini adalah analitik observasional dengan pendekatan retrospektif. Data diambil dari rekam medis pasien yang dirawat inap pada periode September-Desember 2020 di RSUD Dr. Zainoel Abidin dengan teknik total sampling. Hasil penelitian ini diperoleh jenis kelamin terbanyak laki-laki yaitu 272 pasien (55,6%), rentang usia terbanyak 46-65 tahun (55,4%), domisili asal terbanyak dari Kota Banda Aceh 218 pasien (44,6%) serta profesi terbanyak yaitu wiraswasta sebanyak 127 pasien (26%). Derajat keparahan sedang paling sering dijumpai sebanyak 265 pasien (54,2%). Hasil data komorbid didapatkan 237 pasien (48,5%) dimana 85 (17,4%) pasien Hipertensi, 157 (32,1%) pasien Diabetes Melitus, 3 (0,6%) pasien PPOK, 21 (4,3%) pasien CKD, 40 (8,2%) pasien Obesitas. Luaran pasien yang dirawat didapatkan meninggal 107 pasien (21,9%). Hasil analisis data menggunakan uji Chi-Square diperoleh nilai p sebesar 0,179 dan untuk hubungan masing-masing komorbid didapatkan nilai p sebesar 0,644 pada Hipertensi, 0,393 pada Diabetes milletus, 0,630 pada PPOK, 0,194 pada CKD serta 0,455 pada obesitas. Dari hasil analisis data disimpulkan bahwa tidak terdapat hubungan signifikan antara faktor komorbid dengan luaran pasien COVID-19 di RSUD Dr. Zainoel Abidin Banda Aceh.

Kata Kunci : Faktor Komorbid, Luaran pasien COVID-19, Hipertensi, Diabetes Mellitus, PPOK, CKD, Obesitas

ABSTRACT The pandemic caused by infection of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) or better known as Coronavirus Disease 2019 (COVID-19) is still ongoing in various countries. Several previous studies have found that patients with COVID-19 have a high prevalence of having comorbid factors. In addition, comorbidity is also one of the factors that might increase the risk of disease severity and poor outcome. This study aims to determine the relationship between comorbid factors with the outcome of COVID-19 patients. This study used analytical observational design with retrospective approachment. The study was conducted by taking patients who were hospitalized in between September-December 2020 at RSUD Dr. Zainoel Abidin medical record data with total sampling technique. The results showed that the most frequent gender were male 272 patients (55.6%), the most age range was between 46-65 years (55.4%), the most domicile was from Banda Aceh City 218 patients (44.6 %) and the most professions are self-employed as many as 127 patients (26%). Moderate severity was the most common 265 patients (54.2%). The results for comorbid data showed that 237 patients (48.5%) have comorbidity of which 85 (17.4%) patients with hypertension, 157 (32.1%) patients with diabetes mellitus, 3 (0.6%) patients with COPD, 21 (4.3%) patients with CKD, 40 (8.2% ) patients with obesity. Outcome of patients who were treated found 107 patients were died (21.9%). The results of data analysis using the Chi-Square test obtained a p-value of 0.179 and for the relationship of each comorbid, a p-value of 0.644 was obtained in hypertension, 0.393 in Diabetes mellitus, 0.630 in COPD, 0.194 in CKD and 0.455 in obesity. From the results of the data analysis, it was concluded that there was no significant relationship between comorbid factors and the outcome of COVID-19 patients at RSUD Dr. Zainoel Abidin Banda Aceh. Keywords: Comorbid factors, Outcome of COVID-19 patients, Hypertension, Diabetes Mellitus, COPD, CKD, Obesity