Electronic Theses and Dissertation

Tumor atau neoplasma merupakan massa sel abnormal dalam tubuh disebabkan oleh sel tumor terus membelah tanpa koordinasi dengan jaringan sekitarnya. Penelitian ini bertujuan untuk identifikasi tumor berdasarkan klasifikasi dan mampu menamai tumor berdasarkan jaringan asal pembentuknya. Kadaver anjing lokal dilakukan pemeriksaan keadaan luar, patologi anatomi dan sediaan histopatologi. Pemeriksaan keadaan luar ditemukan selaput lendir mata dan mulut ikterus. Hasil pemeriksaan, organ hati bengkak berbentuk massive, konsistensi padat, dan ikterus. Ginjal bengkak dan anemis. Paru-paru bengkak, konsistensi padat, ada foci nekrotik, ada krepitasi dan mengapung. Limpa bengkak dan infark bagian tepi berwarna merah tua dan lunak. Histopatologi dengan pewarnaan hematoksilin dan eosin, organ hati ditemukan banyak sel fibroblast berbentuk spindle, sel nekrosis dan angiogenesis. Ginjal terlihat sel fibroblast berbentuk spindle dan glomerulus nekrosis. Paru terlihat sedikit sel fibroblast berbentuk spindle dan emfisema. Limpa terlihat sel fibroblast berbentuk spindle, pulpa alba dan pulpa rubra bergabung serta trabekula hiperplasia. Pewarnaan Masson’s Trichrome memperlihatkan massa kolagen pada hati. Tumor yang ditemukan pada kadaver anjing didiagnosa fibrosarkoma hepatis yang bermetastasis.

Kata kunci: Fibroblast, fibrosarkoma hepatis, tumor

Tumor or neoplasm are masses of abnormal cells in the body caused by tumor cells that continue to divide without coordination with the surrounding tissue. This study aims to identify tumors based on classification and to be able to name tumors based on the tissue of origin. Local dog cadaver was examined externally, anatomical pathology and histopathological preparation. External examination found the mucous membranes of the eyes and mouth to be icterus. The results of the examination showed that the liver was swollen, massive in shape, dense in consistency, and jaundiced. Swollen and anemic kidneys. The lungs are swollen, the consistency is dense, there are necrotic foci, there are crepitations and floats. Swollen spleen and infarct edges are dark red and tender. Histopathology with hematoxylin and eosin staining, liver organ found many spindle-shaped fibroblast cells, necrosis cells and angiogenesis. Kidneys showed spindle-shaped fibroblast cells and glomerular necrosis. The lungs show scant spindle-shaped fibroblast cells and emphysema. The spleen shows spindle-shaped fibroblast cells, white pulp and rubra pulp combined and trabecular hyperplasia. Masson's Trichrome stain shows collagen masses in the liver. A tumor found in a canine cadaver was diagnosed as metastatic hepatic fibrosarcoma. Keywords: Fibroblast, hepatic fibrosarcoma, tumor