Electronic Theses and Dissertation

Penelitian ini bertujuan untuk mensintesis dan mengkarakterisasi nanobiokomposit TiO₂ termodifikasi ekstrak Curcuma zedoaria sebagai kandidat material recovery gigi berbasis bioaktif dan ramah lingkungan. Sintesis dilakukan melalui metode solution mixing dan crosslink berbasis green synthesis, dengan ekstrak Curcuma zedoaria berperan sebagai agen bioaktif sekaligus penstabil. Karakterisasi material meliputi FTIR, GC-MS, XRD, SEM-EDS, dan Particle Size Analyzer (PSA). Hasil FTIR menunjukkan keberadaan gugus fungsi -OH, C=O, dan C-O dari senyawa bioaktif Curcuma zedoaria serta pita khas Ti-O dan Ti-O-Ti, disertai pergeseran pita yang mengindikasikan terbentuknya interaksi kimia antarmuka TiO₂-organik. Analisis GC-MS mengidentifikasi senyawa dominan seperti curdione, curcumenol, epicurzerenone, dan eucalyptol yang tetap terdeteksi setelah proses crosslink, menandakan stabilitas senyawa bioaktif dalam sistem biokomposit. Pola XRD menunjukkan karakter semi-kristalin dengan fase anatase TiO₂ yang masih terpelihara, ditandai oleh puncak difraksi utama pada 2θ ≈ 25°, dengan pelebaran puncak yang mengindikasikan ukuran kristalit nano dan dispersi yang baik dalam matriks organik. Citra SEM memperlihatkan morfologi yang lebih homogen dibandingkan ekstrak murni, sementara analisis EDS mengonfirmasi distribusi unsur Ti, O, dan C yang merata. Hasil PSA menunjukkan distribusi ukuran partikel yang relatif sempit dengan nilai D25 = 0,190 µm, D50 = 0,224 µm, dan D75 = 0,268 µm, mengindikasikan berkurangnya aglomerasi dan stabilitas dispersi partikel akibat proses crosslink. Secara keseluruhan, hasil karakterisasi saling mendukung dan menunjukkan bahwa nanobiokomposit TiO₂-Curcuma zedoaria memiliki sifat fisik, kimia, dan struktural yang konsisten serta berpotensi diaplikasikan sebagai material recovery gigi berbasis bioaktif dan berkelanjutan.

This study aimed to synthesize and characterize a TiO₂-Curcuma zedoaria nano biocomposite as a bioactive and environmentally friendly candidate for dental recovery materials. The nano biocomposite was synthesized using a solution mixing and crosslinking approach based on green synthesis, in which Curcuma zedoaria extract functioned as both a bioactive agent and a stabilizer. Material characterization was performed using Fourier Transform Infrared Spectroscopy (FTIR), Gas Chromatography-Mass Spectrometry (GC-MS), X-ray Diffraction (XRD), Scanning Electron Microscopy coupled with Energy Dispersive Spectroscopy (SEM-EDS), and Particle Size Analysis (PSA). FTIR analysis confirmed the presence of functional groups such as -OH, C=O, and C-O originating from bioactive compounds of Curcuma zedoaria, along with characteristic Ti-O and Ti-O-Ti bands. Shifts in absorption peaks indicated the formation of interfacial chemical interactions between TiO₂ and the organic matrix. GC-MS analysis identified dominant bioactive compounds, including curdione, curcumenol, epicurzerenone, and eucalyptol, which remained detectable after the crosslinking process, demonstrating the stability of bioactive constituents within the nanobiocomposite system. XRD patterns revealed a semi-crystalline structure with a preserved anatase phase of TiO₂, characterized by a main diffraction peak at 2θ ≈ 25°, while peak broadening suggested nanoscale crystallite size and good dispersion within the organic matrix. SEM observations showed a more homogeneous morphology compared to the pristine extract, and EDS analysis confirmed a uniform distribution of Ti, O, and C elements. PSA results indicated a relatively narrow particle size distribution with D25 = 0.190 µm, D50 = 0.224 µm, and D75 = 0.268 µm, reflecting reduced particle agglomeration and improved dispersion stability due to the crosslinking process. Overall, the integrated characterization results demonstrate that the TiO₂-Curcuma zedoaria nanobiocomposite exhibits consistent physicochemical and structural properties, supporting its potential application as a sustainable bioactive dental recovery material.