Electronic Theses and Dissertation

Rheumatoid arthritis/ra merupakan penyakit autoimun kronis yang ditandai oleh inflamasi sistemik dan kerusakan sendi progresif. pemeriksaan rheumatoid factor/rf dan laju endap darah/led digunakan untuk menilai aktivitas inflamasi pada penderita. tujuan penelitian untuk mengetahui perbandingan rheumatoid factor dengan laju endap darah pada penderita rheumatoid arthritis di rsud dr. zainoel abidin banda aceh. desain observasional analitik dengan pendekatan cross sectional menggunakan data rekam medis periode januari 2022 sampai desember 2024. sampel berjumlah 222 penderita yang memenuhi kriteria inklusi dan eksklusi dengan teknik total sampling. analisis perbandingan menggunakan uji independent sample test dengan tingkat signifikansi 0,05. hasil menunjukkan sebagian besar penderita berjenis kelamin perempuan sebanyak 197 orang (88,7%). rheumatoid factor/rf negatif lebih banyak yaitu 146 penderita (65,8%) dibandingkan positif sebanyak 76 penderita (34,2%). nilai rata-rata laju endap darah pada rf positif lebih tinggi yaitu 63,05 mm/jam dibandingkan negatif yaitu 47,94 mm/jam. sebagian besar rf positif memiliki led >20 mm/jam sebanyak 68 penderita (89,5%). hasil uji independent sample t-test menunjukkan p=0,001 (p

Rheumatoid arthritis/RA is a chronic autoimmune disease characterized by systemic inflammation and progressive joint damage. Rheumatoid factor/RF and erythrocyte sedimentation rate/ESR are used to assess inflammatory activity in patients. The aim of this study was to determine the comparison between rheumatoid factor and erythrocyte sedimentation rate in patients with rheumatoid arthritis at RSUD dr. Zainoel Abidin Banda Aceh. An analytical observational study with a cross-sectional design was conducted using medical record data from January 2022 to December 2024. The sample consisted of 222 patients who met the inclusion and exclusion criteria and were selected using a total sampling technique. Data analysis was performed using the independent samples t-test with significance level of 0,05. The results showed that most patients were female 197 patients (88.7%). Rheumatoid factor/RF negative results were more frequent 146 patients (65.8%) than positive results 76 patients (34.2%). The mean ESR was higher in the RF positive group 63.05 mm/hour than in the RF negative group 47.94 mm/hour. Most RF positive patients had an ESR >20 mm/hour 68 patients (89.5%). The independent samples t-test showed a p-value of 0,001 (p